Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans | Nature Communications
Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans | Nature Communications
Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans | Nature Communications,C9orf72 functions in the nucleus to regulate DNA damage repair | Cell Death & Differentiation,The DAXX tax: C9orf72 DNA repeat expansions drive gain- and loss-of-function pathology in c9FTD/ALS: Neuron,Disruption of nuclear speckle integrity dysregulates RNA splicing in C9ORF72-FTD/ALS: Neuron,Disruption of nuclear speckle integrity dysregulates RNA splicing in C9ORF72-FTD/ALS: Neuron,